Rotting by radicals--the role of cellobiose oxidoreductase?
نویسندگان
چکیده
Cellobiose oxidoreductase is a flavocytochrome secreted by wood-rotting fungi. The structure and functional role of the enzyme are reviewed, and a mechanism through which the enzyme produces superoxide, ferrous iron and hydrogen peroxide is proposed. The reactions of hydroxyl radicals formed by Fenton chemistry are discussed in the context of lignocellulose biodegradation.
منابع مشابه
Characterization of Cellobiose Dehydrogenase from a Biotechnologically Important Cerrena unicolor Strain
Cellobiose dehydrogenase (CDH), a secreted flavocytochrome produced by a number of wood-degrading fungi, was detected in the culture supernatant of a biotechnologically important strain of Cerrena unicolor grown in a modified cellulose-based liquid medium. The enzyme was purified as two active fractions: CuCDH-FAD (flavin domain) (1.51-fold) with recovery of 8.35 % and CuCDH (flavo-heme enzyme)...
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 31 Pt 6 شماره
صفحات -
تاریخ انتشار 2003